ORGAN

LESION

7 DAY

14 DAY

Testis

Necrosis

2.67 ± 0.24

2.67 ± 0.24

Atrophy

1.60 ± 1.12

2.20 ± 0.68

Congestion

0.80 ± 0.86

0.73 ± 0.80

ICI

2.47 ± 0.52

2.27 ± 0.59

Average

1.88 ± 1.07

1.97 ± 0.97

Epididymis

Inflm. cell infiltration

1.33 ± 0.90

1.07 ± 0.70

Average

1.33 ± 0.90

1.07 ± 0.70

Prepuce

Necrosis

0.40 ± 0.51

0.93 ± 0.59^a

Congestion

1.27 ± 0.88

0.93 ± 0.96

Inflm. cell infiltration

1.73 ± 1.10

1.80 ± 0.68

Average

1.13 ± 1.01

1.27  ± 0.84

Bulbourethral

Necrosis

-

-

Atrophy

-

-

Haemorrhage

-

-

Congestion

-

-

Inflam. cell infiltration

-

-

Hyperplasia

-

-

Average

-

-

Seminal Vesicle

Congestion

0.67 ± 0.49

0.80 ± 0.77

Inflam. cell infiltration

0.73 ± 0.70

1.07 ± 0.80

Hyperplasia

-

-

Average

0.70 ± 0.59

0.93 ± 0.78

Submandibular LN

Congestion

0.87 ± 0.92

1.27 ± 0.70

Inflam. cell infiltration

0.60 ± 0.51

0.93 ± 0.59

Hyperplasia

0.27 ± 0.46

1.13 ± 0.83^a

Average

0.58 ± 0.59

1.11 ± 0.71^a

Pre-scapular LN

Haemorrhage

0.53 ± 0.52

0.67 ± 0.82

Congestion

0.73 ± 0.70

0.67 ± 0.72

Inflam. cell infiltration

0.53 ± 0.52

0.73 ± 0.80

Hyperplasia

0.53 ± 0.64

1.20 ± 1.01^a

Average

0.58 ± 0.69

0.82 ± 0.85

Supra-mammary LN

Inflam. cell infiltration

0.47 ± 0.52

0.80 ± 0.68

Hyperplasia

-

-

Average

0.47 ± 0.52

0.80 ± 0.68

Liver

Congestion

0.00 ± 0.00

2.60 ± 0.51^a

Inflam. cell infiltration

0.00 ± 0.00

1.00 ± 0.53^a

Hyperplasia

-

-

Average

0.00 ± 0.00

2.07 ± 0.91^a